Garg, Ankur https://orcid.org/0000-0002-9868-2550
Desousa, Brandon R.
Roy, Raju https://orcid.org/0000-0001-9662-3568
Flis, Amy https://orcid.org/0009-0006-8303-8996
Blume, Skyler Y.
Abe, Yohei
Melo, Arthur A.
Cupo, Ryan R.
Grigorean, Gabriela https://orcid.org/0000-0001-5693-0846
Southworth, Daniel R. https://orcid.org/0000-0001-7108-9389
Shorter, James https://orcid.org/0000-0001-5269-8533
Jain, Isha H. https://orcid.org/0000-0001-5053-0964
Funding for this research was provided by:
U.S. Department of Health & Human Services | National Institutes of Health (DP5OD026398)
United States Department of Defense | United States Army | Army Medical Command | Congressionally Directed Medical Research Programs (PR230499-HT94252410163)
United States Department of Defense | United States Army | Army Medical Command | Congressionally Directed Medical Research Programs (PR230499-HT94252410163)
United States Department of Defense | United States Army | Army Medical Command | Congressionally Directed Medical Research Programs (PR230499-HT94252410163)
Esther A. and Joseph Klingenstein Fund (N/A)
Esther A. and Joseph Klingenstein Fund (N/A)
W. M. Keck Foundation
Dave Wentz, Gift
California Institute for Regenerative Medicine (N/A)
HD@Penn Initiativ
N/A
U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (R01GM138690)
U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (R01GM099836)
Article History
Received: 27 July 2025
Accepted: 11 June 2026
First Online: 8 July 2026
Competing interests
: I.H.J. has patents related to hypoxia therapy, including US20250319119A1 and US12544403B2. The other authors declare no competing interests.