Qiao, Mengyun https://orcid.org/0000-0002-5157-1079
McGurk, Kathryn A.
Wang, Shuo
Matthews, Paul M. https://orcid.org/0000-0002-1619-8328
O’Regan, Declan P.
Bai, Wenjia https://orcid.org/0000-0003-2943-7698
Funding for this research was provided by:
RCUK | Engineering and Physical Sciences Research Council (EP/W01842X/1, EP/W01842X/1)
British Heart Foundation (FS/IPBSRF/22/27059, RE/18/4/34215, RG/19/6/34387, RE/24/130023, CH/P/23/80008)
Shanghai International Science and Technology (23410710400)
Alzheimer's Society
RCUK | Medical Research Council (MC_UP_1605/13)
Article History
Received: 20 September 2024
Accepted: 7 April 2025
First Online: 19 May 2025
Competing interests
: D.P.O. has consulted for Bayer AG and Bristol-Myers-Squibb. K.A.M. has consulted for Checkpoint Capital LP. None of these activities is directly related to the work presented here. P.M.M. has received consultancy or speaker fees from Roche, Merck, Biogen, Rejuveron, Sangamo, Nodthera and Novartis. P.M.M. has received research or educational funds from Biogen, Novartis, Merck and GlaxoSmithKline. The other authors declare no competing interests.