Pontikos, Nikolas https://orcid.org/0000-0003-1782-4711
Woof, William A. https://orcid.org/0000-0001-7555-329X
Lin, Siying https://orcid.org/0000-0003-1122-8396
Ghoshal, Biraja https://orcid.org/0000-0001-5456-2197
Mendes, Bernardo S. https://orcid.org/0009-0002-0416-6852
Veturi, Advaith https://orcid.org/0000-0001-6158-8408
Nguyen, Quang https://orcid.org/0000-0003-2665-3125
Javanmardi, Behnam https://orcid.org/0000-0002-9317-6114
Georgiou, Michalis
Hustinx, Alexander https://orcid.org/0000-0003-4592-3979
Ibarra-Arellano, Miguel A. https://orcid.org/0000-0001-8411-4854
Moghul, Ismail https://orcid.org/0000-0003-3653-2327
Liu, Yichen
Pfau, Kristina
Pfau, Maximilian
Shah, Mital https://orcid.org/0000-0001-7496-6121
Yu, Jing
Al-Khuzaei, Saoud https://orcid.org/0000-0002-2779-3202
Wagner, Siegfried K. https://orcid.org/0000-0003-4915-4353
Daich Varela, Malena https://orcid.org/0000-0003-4960-4510
Cabral de GuimarĂ£es, Thales Antonio https://orcid.org/0000-0002-7936-6851
Sen, Sagnik https://orcid.org/0000-0001-5835-5371
Naik, Gunjan https://orcid.org/0000-0003-1296-1362
Sumodhee, Dayyanah https://orcid.org/0000-0001-7274-6088
Fu, Dun Jack https://orcid.org/0000-0003-2852-6912
Kabiri, Nathaniel https://orcid.org/0000-0003-3684-0020
Furman, Jennifer https://orcid.org/0000-0002-0622-6989
Liefers, Bart https://orcid.org/0000-0002-2763-6426
Lee, Aaron Y.
De Silva, Samantha R. https://orcid.org/0000-0002-4455-2814
Marques, Caio https://orcid.org/0000-0002-3992-6965
Motta, Fabiana
Fujinami-Yokokawa, Yu https://orcid.org/0000-0001-7555-5797
Hardcastle, Alison J. https://orcid.org/0000-0002-0038-6770
Arno, Gavin
Lorenz, Birgit https://orcid.org/0000-0002-9737-8127
Herrmann, Philipp
Fujinami, Kaoru
Sallum, Juliana https://orcid.org/0000-0002-7206-4447
Madhusudhan, Savita
Downes, Susan M. https://orcid.org/0000-0001-7373-2665
Holz, Frank G. https://orcid.org/0000-0001-8019-9272
Balaskas, Konstantinos https://orcid.org/0000-0001-5679-4186
Webster, Andrew R. https://orcid.org/0000-0001-6915-9560
Mahroo, Omar A. https://orcid.org/0000-0003-1254-0832
Krawitz, Peter M. https://orcid.org/0000-0002-3194-8625
Michaelides, Michel https://orcid.org/0000-0002-1552-7046
Article History
Received: 9 September 2024
Accepted: 11 April 2025
First Online: 18 June 2025
Competing interests
: N.P., W.W., M.M. and A.R.W. are patent holders of PCT/EP2023/076614 filed by UCL Business. I.M. is a cofounder, share-holder and director of Phenopolis Ltd, the software company that developed . N.P. is a cofounder and former share-holder and director of Phenopolis Ltd. A.Y.L. reports grants from Santen, personal fees from Genentech, personal fees from US FDA, personal fees from Johnson and Johnson, grants from Carl Zeiss Meditec, personal fees from Gyroscope, non-financial support from Microsoft and grants from Regeneron, outside the submitted work. M.M. has received consultancy or advisory board fees from MeiraGTx, Janssen Pharmaceuticals, Saliogen and Octant; travel grants from MeiraGTx and Janssen Pharmaceuticals and stock options from MeiraGTx. The other authors declare no competing interests.