Deltadahl, Simon https://orcid.org/0009-0009-8437-7705
Gilbey, Julian https://orcid.org/0000-0002-5987-5261
Van Laer, Christine
Boeckx, Nancy
Leers, Mathie P. G. https://orcid.org/0000-0001-5186-5600
Freeman, Tanya
Aiken, Laura
Farren, Timothy
Smith, Matthew
Zeina, Mohamad https://orcid.org/0000-0002-8119-1931
MacDonald, Stephen
Gleghorn, Daniel
,
Schut, Martijn
Asselbergs, Folkert
Kar, Sujoy
Williams, Sophie
Koh, Mickey
Henskens, Yvonne
de Wit, Norbert
D’Alessandro, Umberto
Bah, Bubacarr
Secka, Ousman
Gupta, Rajeev
Trompeter, Sara
van Laer, Christine
Awandare, Gordon A.
Sarpong, Kwabena
Amenga-Etego, Lucas
Ouwehand, Willem H.
Rudd, James H. F.
Rudd, James HF https://orcid.org/0000-0003-2243-3117
Piazzese, Concetta https://orcid.org/0000-0002-3605-1809
Taylor, Joseph
Gleadall, Nicholas
Schönlieb, Carola-Bibiane
Sivapalaratnam, Suthesh
Roberts, Michael https://orcid.org/0000-0002-3484-5031
Nachev, Parashkev https://orcid.org/0000-0002-2718-4423
Funding for this research was provided by:
Trinity Challenge
Trinity Challenge Barts Health NHS Trust
Trinity Challenge British Heart Foundation
Trinity Challenge Barts Health
Trinity Challenge Cambridge University Hospitals NHS Blood and Transplant
Trinity Challenge Wellcome Trust
Cambridge University Hospitals
Article History
Received: 12 November 2024
Accepted: 4 September 2025
First Online: 19 November 2025
Competing interests
: P.N. is a co-founder of Hologen, a healthcare generative AI company with a focus on late-stage interventional agent development. M.R. is also a consultant and S.D. is an employee of Hologen. M.R. is co-founder of Octiocor, a company specializing in AI-based analysis of intracoronary imaging. The other authors declare no competing interests.