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Article History

Received: 9 July 2019

Accepted: 20 November 2019

First Online: 13 January 2020

Competing interests

: V.A. receives research funding from Bristol-Meyer Squibb. P.M.F. receives research funding for clinical trials from Bristol-Myers Squibb, AstraZeneca/MedImmune, Kyowa, Corvus and Novartis and is a consultant/advisory board member for AbbVie, AstraZeneca, Bristol-Meyers Squibb, Boehringer Ingelheim, Celgene, EMD Serono, Inivata, Janssen, Lilly, Merck, and Novartis. J.R.W. is founder and owner of Resphera Biosciences, and is a consultant for Personal Genome Diagnostics. J.N. receives research funding from Merck, AstraZeneca/MedImmune, Kyowa and Calithera and is a consultant/advisory board member of Bristol-Myers Squibb, AstraZeneca/MedImmune and Takeda. C.L.H. is a consultant/advisory board member for AbbVie, Bristol-Myers Squibb and Genentech, receives research funding from Merrimack, GlaxoSmithKline, AbbVie, Bristol-Myers Squibb, and GlaxoSmithKline. B.L. is a consultant/advisory board member of AstraZeneca, Celgene, Genentech Rouche, Eli Lilly and Takeda and receives research funding from Celgene and Boehringer Ingleheim. J.R.B. receives research grants from Bristol-Myers Squibb, AstraZeneca/MedImmune and Merck and is a consultant/advisory board member for Bristol-Myers Squibb, AstraZeneca/MedImmune and Merck. M.V.B. is a paid consultant for Cepheid Inc. J.I. owns LumaCyte, LLC. Stock. D.M.P. receives research support from Bristol-Myers Squibb, Compugen and Potenza Therapeutics and is a consultant for Aduro Biotech, Amgen, AstraZeneca/Medimmune, Bayer, Compugen, DNAtrix, Five Prime, GlaxoSmithKline, ImmuneXcite, Jounce Therapeutics, Neximmune, Pfizer, Rock Springs Capital, Sanofi and Vesuvius/Tizona. V.E.V. is a founder of Personal Genome Diagnostics, a member of its Scientific Advisory Board and Board of Directors, and owns Personal Genome Diagnostics stock, which are subject to certain restrictions under university policy. V.E.V. is an advisor to Takeda Pharmaceuticals. Within the last 5 years, V.E.V. has been an advisor to Daiichi Sankyo, Janssen Diagnostics and Ignyta. The terms of these arrangements are managed by Johns Hopkins University in accordance with its conflict of interest policies.