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Global loss of promoter–enhancer connectivity and rebalancing of gene expression during early colorectal cancer carcinogenesis

Crossref DOI link: https://doi.org/10.1038/s43018-024-00823-z

Published Online: 2024-10-30

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Zhu, Yizhou

Lee, Hayan https://orcid.org/0000-0003-0571-3192
White, Shannon

Weimer, Annika K. https://orcid.org/0000-0001-9944-8769
Monte, Emma

Horning, Aaron https://orcid.org/0000-0003-3247-0798
Nevins, Stephanie A.

Esplin, Edward D. https://orcid.org/0000-0001-9205-3756
Paul, Kristina https://orcid.org/0000-0003-0767-4617
Krieger, Gat

Shipony, Zohar

Chiu, Roxanne

Laquindanum, Rozelle

Karathanos, Thomas V. https://orcid.org/0000-0003-1754-3872
Chua, Melissa W. Y.

Mills, Meredith

Ladabaum, Uri

Longacre, Teri

Shen, Jeanne https://orcid.org/0000-0002-1519-0308
Jaimovich, Ariel

Lipson, Doron

Kundaje, Anshul https://orcid.org/0000-0003-3084-2287
Greenleaf, William J. https://orcid.org/0000-0003-1409-3095
Curtis, Christina

Ford, James M.

Snyder, Michael P. https://orcid.org/0000-0003-0784-7987
Funding

Funding for this research was provided by:

U.S. Department of Health & Human Services | NIH | National Cancer Institute (1U2CCA233311, 1U2CCA233311, 1U2CCA233311, 1U2CCA233311, 1U2CCA233311, 1U2CCA233311)
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Text and Data Mining valid from 2024-10-30

Version of Record valid from 2024-10-30
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Article History

Received: 7 March 2024

Accepted: 9 August 2024

First Online: 30 October 2024

Change Date: 26 January 2025

Change Type: Correction

Change Details: A Correction to this paper has been published:

Change Details: https://doi.org/10.1038/s43018-025-00915-4

Competing interests

: G.K., A.J., D.L. and Z.S. are employees and shareholders of Ultima Genomics. M.P.S is a cofounder and scientific advisor of Personalis, Qbio, SensOmics, January AI, Mirvie, Protos, NiMo and Onza and is on the advisory board of Genapsys. E.D.E. is an employee and stockholder of Invitae and an advisor and stockholder of Taproot Health and Exir Bio. W.J.G. has affiliations with Guardant Health (consultant and scientific advisory board), Protillion Biosciences (Scientifica cofounder) and 10x and has licensed patents associated with ATAC-seq. All other authors declare no competing interests.

Updates are available Correction dated 2025-01-26

Click to view Correction: https://doi.org/10.1038/s43018-025-00915-4