Sekiya, Motohiro https://orcid.org/0000-0002-5170-9699
Kainoh, Kenta
Chen, Wanpei
Yamazaki, Daichi
Tsuyuzaki, Tomomi
Kobari, Yuto
Nakata, Ayumi
Saito, Kenji
Aono-Soma, Nao
Majid, Ali
Ohno, Hiroshi
Miyamoto, Takafumi
Matsuzaka, Takashi https://orcid.org/0000-0002-5898-3463
Nakajima, Rikako
Matsuda, Takaaki https://orcid.org/0009-0000-8780-8536
Murayama, Yuki
Sugano, Yoko
Osaki, Yoshinori https://orcid.org/0000-0003-1425-7790
Iwasaki, Hitoshi
Shimano, Hitoshi https://orcid.org/0000-0002-5562-5572
Funding for this research was provided by:
Japan Agency for Medical Research and Development (JP18gm5910007, JP25gm6710004, JP22ek0210175)
MEXT | Japan Society for the Promotion of Science (20K08855, 23K18270)
Takeda Science Foundation
Ono Medical Research Foundation
Manpei Suzuki Diabetes Foundation
Japan Diabetes Foundation
Article History
Received: 7 March 2025
Accepted: 28 August 2025
First Online: 8 October 2025
Competing interests
: The authors declare that a domestic patent application (patent application no. 2025-012235) related to this work has been filed by the University of Tsukuba, with M.S. as an inventor. The patent is under review and has not yet been granted. The other authors declare no competing interests.