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Article History

Received: 31 January 2021

Accepted: 30 November 2021

First Online: 12 January 2022

Change Date: 20 January 2022

Change Type: Update

Change Details: The original version of this Article was updated shortly after publication because the editorial summary text (Nguyen et al. describe the clinical validation of the ENHANCE system, a method to detect SARS-CoV-2 based on engineered crRNAs for Cas12a and preceded by an RT-LAMP amplification step. Authors also describe the development and clinical validation of a version of this system, ENHANCEv2, that can be lyophilized and that uses another mutated Cas12a for further signal amplification.) that should accompany the article on the journal’s website, was inadvertently included as part of the Plain language summary. The error has now been corrected in the HTML and PDF versions of the Article.

Competing interests

: P.K.J. and L.T.N. are listed as inventors on the multiple patent applications related to the content of this work. P.K.J. is a co-founder of Genable Biosciences, LLC. The remaining authors declare no competing interests.