Holste, Gregory http://orcid.org/0000-0002-5657-3081
Oikonomou, Evangelos K.
Mortazavi, Bobak J. http://orcid.org/0000-0002-2655-2095
Wang, Zhangyang
Khera, Rohan http://orcid.org/0000-0001-9467-6199
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (K23HL153775)
Doris Duke Charitable Foundation (2022060)
Article History
Received: 23 September 2023
Accepted: 31 May 2024
First Online: 6 July 2024
Competing interests
: The authors declare the following competing interests: E.K.O is a co-inventor of the U.S. Provisional Patent Application 63/177,117, a co-founder of Evidence2Health, and reports a consultancy and stock option agreement with Caristo Diagnostics Ltd (Oxford, U.K.), all unrelated to the current work. B.J.M. has a pending patent on predictive models using electronic health records (US20180315507A1). R.K. is an Associate Editor at JAMA and receives research support, through Yale University, from Bristol-Myers Squibb Novo Nordisk, and BridgeBio. He is also a coinventor of U.S. Pending Patent Applications WO2023230345A1, US20220336048A1, 63/346,610, 63/484,426, 63/508,315, 63/580,137, 63/606,203, 63/619,241, and 63/562,335, unrelated to the current work. He is also a co-founder of Ensight-AI andĀ Evidence2Health, precision health platforms to improve disease diagnosis andĀ evidence-based cardiovascular care. All other authors declare no competing interests.