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Authors
Schiabor Barrett, Kelly M. https://orcid.org/0000-0001-6194-787X
Telis, Natalie
McEwen, Lisa M.
Burrows, Evanette K.
Khuder, Basil
Judge, Daniel P. https://orcid.org/0000-0002-3407-0248
Pawloski, Pamala A. https://orcid.org/0000-0002-1005-5764
Grzymski, Joseph J. https://orcid.org/0000-0003-2646-8958
Washington, Nicole L. https://orcid.org/0000-0001-8936-9143
Bolze, Alexandre https://orcid.org/0000-0001-7399-2766
Cirulli, Elizabeth T. https://orcid.org/0000-0001-7808-2809
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Article History
Received: 7 November 2023
Accepted: 4 November 2024
First Online: 20 November 2024
Competing interests
: The authors declare the following competing interests: KMSB, NT, BK, LMM, NLW, AB and ETC are all employees of Helix. EKB is an employee at Johnson and Johnson, however, at the time of writing she was affiliated with Helix. A patent has been filed by Helix for the Power Window analysis technique with ETC, KMSB, and NLW as inventors, and its current status is unpublished (application number 17575894). JJG is employed by UNR and Renown Health and has received funding from Gilead Sciences for work not related to this study. DPJ has received consulting fees from Alnylam, Attralus, BridgeBio, Lexeo Therapeutics, and Novo Nordisk in the past 2 years.
: The Helix cohorts were reviewed by Salus IRB (Reliance on Salus for all sites) and approved (approval number 21143), the WCG IRB (Western Institutional Review Board, WIRB-Copernicus Group) and approved (approval number 20224919), the MUSC Institutional Review Board for Human Research and approved (approval number Pro00129083), and the University of Nevada, Reno Institutional Review Board and approved (approval number 7701703417). The UK Biobank study was approved by the North West Multicenter Research Ethics Committee, United Kingdom. All participants gave their informed, written consent before participation. All data used for research were de-identified.
