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Family health history and pharmacogenomics show cross generation premature amitriptyline discontinuation is associated with CYP2C19 loss of-function enrichment

Crossref DOI link: https://doi.org/10.1038/s43856-025-01156-3

Published Online: 2025-11-13

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Magavern, Emma F. https://orcid.org/0000-0003-0699-6411
Marengo, Gabriel https://orcid.org/0009-0004-9420-8239
Megase, Maia

Smedley, Damian https://orcid.org/0000-0002-5836-9850
Caulfield, Mark J. https://orcid.org/0000-0001-9295-3594
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Text and Data Mining valid from 2025-11-13

Version of Record valid from 2025-11-13
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Article History

Received: 4 March 2025

Accepted: 5 September 2025

First Online: 13 November 2025

Competing interests

: The authors declare no competing interests.