Hamada, Shunsuke
Suda, Miharu
Ishida, Katsuyasu
Furihata, Kei
Sogawa, Yoshitaka https://orcid.org/0000-0003-1621-0929
Kumazaki, Masafumi
Takahashi, Kaori
Sakakibara, Sachiko
Matsunaga, Satoko
Jonai, Nao
Nakayama, Tetsuo
Takeshita, Fumihiko https://orcid.org/0009-0001-7124-8877
Funding for this research was provided by:
Ministry of Health, Labour and Welfare (JP21nf0101625)
Japan Agency for Medical Research and Development (JP21nf0101625)
Article History
Received: 16 May 2024
Accepted: 20 October 2025
First Online: 31 March 2026
Competing interests
: The authors declare the following competing interests: S.H., M.S., K.I., K.F., Y.S., M.K., K.T., S.S., S.M., N.J., and F.T. are current employees of Daiichi Sankyo Co., Ltd.; S.H., M.S., Y.S., M.K., K.T., and S.S. hold stock in Daiichi Sankyo Co., Ltd. and N.J. holds patents and other interests with Daiichi Sankyo Co., Ltd. T.N. was a medical advisor at Daiichi Sankyo Co., Ltd. during the conduct of the studies, and has also received remuneration from Takeda Pharmaceutical and EIKEN CHEMICAL and research funding from GSK. The study sponsor (Daiichi Sankyo Co., Ltd.) was involved in the design of the studies, data analysis, and manuscript preparation; MHLW and AMED had no role in study design, data analysis, or preparation of the manuscript.