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Authors
Davies, Helen R. https://orcid.org/0000-0001-6381-3664
Black, Daniella
Kvist, Anders https://orcid.org/0000-0002-1358-0695
Sigurjónsdóttir, Kristín
Bosch, Ana
Bowden, Ramsay https://orcid.org/0000-0003-1138-4452
Memari, Yasin
Chen, Ziqian
Rinaldi, Giuseppe https://orcid.org/0000-0002-5650-6049
Rosengren, Frida
Nacer, Deborah F. https://orcid.org/0000-0002-7117-1371
Veerla, Srinivas https://orcid.org/0000-0001-7328-6239
Hohmann, Lennart https://orcid.org/0000-0002-0281-7140
Nordborg, Nicklas
Häkkinen, Jari https://orcid.org/0000-0002-8466-9179
Vallon-Christersson, Johan https://orcid.org/0000-0002-2195-0385
Borg, Åke https://orcid.org/0000-0002-5793-132X
Nik-Zainal, Serena https://orcid.org/0000-0001-5054-1727
Staaf, Johan https://orcid.org/0000-0001-5254-5115
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Funding
Funding for this research was provided by:
Cancerfonden (CAN 2021/1407, 2024/3591)
Vetenskapsrådet (2021-01800)
the Swedish Breast Cancer Association Swedish governmental funding
Mats Paulsson Foundation the Cancera Foundation Cancerfonden Fru Berta Kamprads stiftelse
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Article History
Received: 15 September 2025
Accepted: 5 January 2026
First Online: 16 February 2026
Competing interests
: S.N.-Z. and H.R.D. hold patents on clinical algorithms of mutational signatures: HRDetect (PCT/EP2017/060294), clinical use of signatures (PCT/EP2017/060289), and clinical predictor (PCT/EP2017/060298). S.N.Z. also holds the following patents: MMRDetect (PCT/EP2022/057387), rearrangement signature methods (PCT/EP2017/060279), hotspots for chromosomal rearrangements (PCT/EP2017/060298), indel signature methods (PCT/EP2024/077959), and PRRDetect algorithm (PCT/EP2024/078030). All other authors declare that they have no competing interests.
