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Synthesis of chiral difluoromethyl cyclopropanes through desymmetric difluoromethylation of cyclopropenes enabled by enantioselective copper catalysis

Crossref DOI link: https://doi.org/10.1038/s44160-025-00809-4

Published Online: 2025-05-22

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Ding, Decai

Chen, Su

Yin, Lingfeng

Ou, Wei-Ting

Krause, Jeanette A.

Cheng, Mu-Jeng https://orcid.org/0000-0002-8121-0485
Liu, Wei https://orcid.org/0000-0001-6249-3179
Funding

Funding for this research was provided by:

U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (R35GM146765)

National Science Foundation (CHE-2237757, CHE-1726092, CHE-1625737)

Herman Frasch Foundation for Chemical Research (926-HF22)
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Text and Data Mining valid from 2025-05-22

Version of Record valid from 2025-05-22
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Article History

Received: 1 October 2024

Accepted: 17 April 2025

First Online: 22 May 2025

Competing interests

: The authors declare no competing interests.

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