Dierickx, Pieterjan https://orcid.org/0000-0002-1709-1477
Zhu, Kun
Carpenter, Bryce J.
Jiang, Chunjie https://orcid.org/0000-0002-3033-092X
Vermunt, Marit W. https://orcid.org/0000-0002-3570-1558
Xiao, Yang
Luongo, Timothy S.
Yamamoto, Tsunehisa
Martí-Pàmies, Íngrid
Mia, Sobuj
Latimer, Mary
Diwan, Abhinav https://orcid.org/0000-0001-7554-4772
Zhao, Juanjuan https://orcid.org/0000-0002-2324-3334
Hauck, Amy K.
Krusen, Brianna
Nguyen, Hoang C. B.
Blobel, Gerd A.
Kelly, Daniel P. https://orcid.org/0000-0002-3811-9491
Pei, Liming https://orcid.org/0000-0002-1924-0333
Baur, Joseph A. https://orcid.org/0000-0001-8262-6549
Young, Martin E.
Lazar, Mitchell A. https://orcid.org/0000-0001-8653-1280
Funding for this research was provided by:
American Heart Association (20POST35210738, 836074, 827529)
European Molecular Biology Organization (ALTF 540-2018)
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (F32HL145923, R01HL128349, R01HL151345, R01HL149159)
U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (F32DK122684-01A1, RO1 DK111495, NIH R01 DK098656, R01DK45586)
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute
U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases
U.S. Department of Defense (W81XWH20-1-0042)
U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute
U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases
JPB Foundation
Article History
Received: 7 August 2021
Accepted: 19 October 2021
First Online: 23 December 2021
Competing interests
: M.A.L. receives research support from Pfizer for unrelated work; serves as an advisory board member for Pfizer and Flare Therapeutics; has consulted for Novartis, Madrigal, Calico and Third Rock; and holds equity in KDAC Therapeutics and Flare Therapeutics. D.P.K. serves as an advisory board member for Pfizer and Amgen. J.A.B. is an inventor on a patent for using NAD<sup>+</sup> precursors in liver injury, is a consultant for Pfizer and Cytokinetics and has received research funding and materials from Elysium Health and Metro International Biotech, both of which have an interest in NAD<sup>+</sup> precursors. No funds or materials from Elysium Health and Metro International Biotech were used to generate any data for this study. The remaining authors declare no competing interests.