Papa, Arianne https://orcid.org/0000-0001-6272-9209
Zakharov, Sergey I.
Katchman, Alexander N.
Kushner, Jared S. https://orcid.org/0000-0003-4821-0990
Chen, Bi-xing
Yang, Lin
Liu, Guoxia
Jimenez, Alejandro Sanchez
Eisert, Robyn J. https://orcid.org/0000-0001-7977-249X
Bradshaw, Gary A. https://orcid.org/0000-0001-9724-6100
Dun, Wen
Ali, Shah R.
Rodriques, Aaron
Zhou, Karen
Topkara, Veli
Yang, Mu
Morrow, John P.
Tsai, Emily J. https://orcid.org/0000-0002-5098-1463
Karlin, Arthur https://orcid.org/0000-0002-4813-752X
Wan, Elaine
Kalocsay, Marian https://orcid.org/0000-0002-4187-5829
Pitt, Geoffrey S. https://orcid.org/0000-0003-2246-0289
Colecraft, Henry M.
Ben-Johny, Manu https://orcid.org/0000-0002-5645-0815
Marx, Steven O. https://orcid.org/0000-0002-0577-6030
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (F31 HL158232, K08 HL151969, K08HL153788, HL155377, HL140934)
Article History
Received: 16 June 2022
Accepted: 29 September 2022
First Online: 14 November 2022
Competing interests
: Columbia University, Harvard University and NY Presbyterian Hospital have filed a patent (WO/2021/003389), which is published and pending review, reporting a FRET-based method for screening small molecules that increase contractility for the treatment of heart failure. Inventors on this patent application are S.O.M., H.M.C., M.K., S.I.Z., A.N.K., M.B.J. and G.L. The FRET-based assay was utilized in this manuscript for assessing the effects of calyculin and whether 3DA-β<sub>2B</sub> and 2DA-β<sub>2B</sub> Ca<sup>2+</sup> channel subunits bind to Rad.