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Authors
Meng, Fansen
Steimle, Jeffrey D. https://orcid.org/0000-0002-1369-9661
Straight, Elizabeth https://orcid.org/0009-0008-2050-4042
Li, Rich G.
Morikawa, Yuka https://orcid.org/0000-0002-4571-8409
Iqbal, Zohaib
Xie, Bing
Wang, Jun
Paltzer, Wyatt G. https://orcid.org/0000-0002-9142-4217
Zhao, Yi
Tsai, Chang-Ru
Liu, Lin
Lim, Maggie
Schack, Rita A.
Ramirez, Daniel https://orcid.org/0009-0002-9582-3968
Carlson, Katherine https://orcid.org/0009-0001-7066-7754
Deshmukh, Vaibhav https://orcid.org/0000-0002-0087-7545
Karch, Jason M. https://orcid.org/0000-0002-3023-7469
Pautler, Robia G.
Li, Xiao https://orcid.org/0000-0001-8527-4438
Martin, James F. https://orcid.org/0000-0002-7842-9857
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Funding
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (HL130804)
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (HL177644)
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (HL173242)
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (HL127717)
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (K99 HL169742)
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (K99HL174827)
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (HL177644)
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (HL173242)
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (HL142704)
American Heart Association (903411)
American Heart Association (24CDA1274610)
American Heart Association (903651)
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Article History
Received: 19 June 2024
Accepted: 3 October 2025
First Online: 13 November 2025
Competing interests
: J.F.M. is a cofounder of Yap Therapeutics. J.F.M. is a coinventor on the following patents associated with this study: patent no. US20200206327A1 titled ‘Hippo pathway deficiency reverses systolic heart failure post-infarction’, applicant: Baylor College of Medicine, inventor: J.F.M., patent granted. It covers Figs. and and Extended Data Figs. – of this article; patent no. US-20220411798-A1 titled ‘Hippo and dystrophin complex signaling in cardiomyocyte renewal’, applicant: Baylor College of Medicine and Texas Heart Institute, inventor: J.F.M., patent granted. It covers Figs. and and Extended Data Figs. – of the present article; and patent no. US-11459565-B2 titled ‘Hippo and dystrophin complex signaling in cardiomyocyte renewal’, applicants: Baylor College of Medicine and Texas Heart Institute, inventor: J.F.M., patent granted. It covers Figs. and and Extended Data Figs. – of the present article. Y.M. is a coinventor on the aforementioned patents associated with this study. The other authors declare no competing interests.
