Narita, Zui C. https://orcid.org/0000-0001-7022-2141
DeVylder, Jordan
Knowles, Gemma
Ando, Shuntaro https://orcid.org/0000-0003-1595-693X
Yamasaki, Syudo https://orcid.org/0000-0002-9016-6404
Miyashita, Mitsuhiro
Stanyon, Daniel
Yamaguchi, Satoshi
Furukawa, Toshiaki A. https://orcid.org/0000-0003-2159-3776
Kasai, Kiyoto
Nishida, Atsushi
Funding for this research was provided by:
University of Tokyo (NA)
MEXT | Japan Science and Technology Agency (JPMJPF2105)
Article History
Received: 6 February 2025
Accepted: 9 July 2025
First Online: 4 August 2025
Competing interests
: T.A.F. reports personal fees from Boehringer-Ingelheim, Daiichi Sankyo, DT Axis, Micron, Shionogi, SONY, and UpToDate, and a grant from DT Axis and Shionogi, outside the submitted work. In addition, T.A.F. has a patent 7448125 and a pending patent 2022-082495, and has licensed intellectual properties for Kokoro-app to Mitsubishi-Tanabe. K.K. reports grants from Teijin, Takeda, Lily, Otsuka, Daiichi Sankyo, Shionogi, Tanabe-Mitsubishi, and Sumitomo; and personal fees from Sumitomo, Meiji-Seika, Ricoh, Fuji-film Wako, Takeda, Otsuka, and Astellas outside the submitted work. The other authors declared no conflicts of interest.
: All procedures were approved by the Institutional Review Boards of the Tokyo Metropolitan Institute of Medical Science (12-35), the University of Tokyo (10057), and the SOKENDAI (2012002). All parents provided written informed consent.