Biesma, H. D.
Soeratram, T. T. D.
van Essen, H. F.
Egthuijsen, J. M. P.
Poell, J. B.
van Dijk, E.
Meershoek - Klein Kranenbarg, E.
Hartgrink, H. H.
van de Velde, C. J. H.
van de Wiel, M. A.
Ylstra, B.
van Grieken, N. C. T.
Funding for this research was provided by:
KWF Kankerbestrijding (KWF2016-2/10613)
Cancer Center Amsterdam (CCA2015-5-24)
Article History
Received: 2 April 2024
Revised: 28 June 2024
Accepted: 2 July 2024
First Online: 19 August 2024
Ethics approval and consent to participate
: This study was in accordance with the Declaration of Helsinki. The D1/D2 trial was approved by the medical ethical committee of the Leiden University Medical Center. In addition, the Dutch Code of Conduct for Responsible Use of Human Tissue allows for the analysis of residual tissue specimens obtained for diagnostic purposes and anonymized publication of the study results [].
: NCTvG has served on the advisory boards of BMS and MSD. Topics were not related to the present study. NCTvG received research grants from the Dutch Cancer Society [grant KWF2016-2/10613] and the Cancer Center Amsterdam [grant CCA2015-5-24], all fees paid to the institute, but related to the present study. NCTvG received research grants from The Netherlands Organization for Health Research and Development (ZonMW), all fees paid to the institute, but not related to the present study. The remaining authors declare that they have no conflict of interest.