Allen, Isaac
Whish, Nancy
Yadav, Siddhartha
Boddicker, Nicholas J.
Drukker, Caroline
van de Beek, Irma
Eccles, Diana M.
Turnbull, Clare
Pharoah, Paul
Antoniou, Antonis C.
Easton, Douglas F.
Couch, Fergus J.
Schmidt, Marjanka K.
Tischkowitz, Marc
Article History
Received: 25 September 2025
Revised: 3 March 2026
Accepted: 5 March 2026
First Online: 3 June 2026
Competing interests
: Fergus J. Couch consulted for Astrazeneca and received research funds from GRAIL. Siddhartha Yadav: Research funding: AstraZeneca (Institution), Exelexis (Institution), Repare Therapeutics (Institution), 858 Therapeutics (Institution), Advisory Board: AstraZeneca (Institution). Antonis C. Antoniou: Listed as creator of the BOADICEA model which has been licensed by Cambridge Enterprise (University of Cambridge) for commercial purposes. Marc Tischkowitz is the Editor-in-Chief of BJC Reports ; he was not involved in any aspect of the handling of this manuscript or any editorial decisions. Remaining authors disclosed no conflicts of interest.
: All methods were performed in accordance with the relevant guidelines and regulations.