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Distinct senotypes in p16- and p21-positive cells across human and mouse aging tissues

Crossref DOI link: https://doi.org/10.1038/s44318-025-00601-2

Published Online: 2025-10-29

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Saul, Dominik https://orcid.org/0000-0002-0673-3710
Jurk, Diana

Doolittle, Madison L

Kosinsky, Robyn Laura

Han, Yeaeun https://orcid.org/0000-0003-1122-3691
Zhang, Xu

Franco, Ana Catarina

Kim, Sung Y

Wyles, Saranya P

Prakash, Y S

Monroe, David G

Ferrucci, Luigi

LeBrasseur, Nathan K https://orcid.org/0000-0002-2002-0418
Robbins, Paul D

Niedernhofer, Laura J

Khosla, Sundeep https://orcid.org/0000-0002-2936-4372
Passos, João F https://orcid.org/0000-0001-8765-1890
Funding

Funding for this research was provided by:

HHS | National Institutes of Health (P01 AG062413)

HHS | National Institutes of Health (R01AG068048; R01AG827; UG3CA26810308; UH3CA268103)

HHS | National Institutes of Health (R01 AG068182)

HHS | National Institutes of Health (R01 AG086085)

HHS | National Institutes of Health (R01 AG055529)

HHS | National Institutes of Health (R01AG82708)

HHS | National Institutes of Health (R01 AG063543)

HHS | National Institutes of Health (R01AG07651)

HHS | National Institutes of Health (U54 AG079754)

HHS | National Institutes of Health (U54 AG076041)

HHS | National Institutes of Health (U19 AG056278)

Hevolution (HR-GRO-23-1199144-8)

National Research Foundation of Korea (2020M3A9D8038014)
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Text and Data Mining valid from 2025-10-29

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Article History

Received: 8 July 2025

Revised: 28 August 2025

Accepted: 30 September 2025

First Online: 29 October 2025

Disclosure and competing interests statement

: The authors declare no competing interests.

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