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Authors
Lyons, Sulayman A
Lea, Micah B S https://orcid.org/0009-0002-6506-7719
Parikh, Mihir
Guo, Zhengzhang https://orcid.org/0009-0008-7280-8566
Kagdi, Samrin
Bisnauth, Abigail R
Pitino, Jonathan R
Ziai, Sabrina
Mir, Negar
Tyrrell, Aidan D
Fu, Yan https://orcid.org/0009-0005-4930-5774
Chen, Chuck T https://orcid.org/0000-0002-1099-4198
Metherel, Adam H
Bazinet, Richard P
Yang, Bin
Knerr, Patrick J
Douros, Jonathan D
Campbell, Jonathan E https://orcid.org/0000-0003-4358-6331
Beaudry, Jacqueline L https://orcid.org/0000-0003-1805-8844
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Funding
Funding for this research was provided by:
Canadian Government | CIHR | Institute of Nutrition, Metabolism and Diabetes
UofT | Banting and Best Diabetes Centre, University of Toronto (Drucker Family Innovation Fund)
Canadian Government | Natural Sciences and Engineering Research Council of Canada
HHS | NIH | NIDDK | Division of Diabetes, Endocrinology, and Metabolic Diseases (DK046492)
HHS | NIH | NIDDK | Division of Diabetes, Endocrinology, and Metabolic Diseases (DK125353)
HHS | NIH | NIDDK | Division of Diabetes, Endocrinology, and Metabolic Diseases (DK123075)
HHS | NIH | NIDDK | Division of Diabetes, Endocrinology, and Metabolic Diseases (DK141090)
Canada Foundation for Innovation (CFI)-Ontario Research Fund
CFI- John R. Evans Leaders Fund
China Scholarship Council
Canada Research Chairs (Brain Lipid Metabolism)
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Article History
Received: 7 May 2025
Revised: 8 August 2025
Accepted: 30 August 2025
First Online: 22 September 2025
Disclosure and competing interests statement
: PJK, BY, and JDD are former employees and shareholders of Novo Nordisk. JEC receives funding for basic science from Eli Lilly, Novo Nordisk, Merck, Structure Therapeutics, Fractyl Health, and Prostasis. JEC has served as an advisor in the past 12 months to Arrowhead Pharma, Boehringer Ingelheim, Protagonist, Prostasis, Septerna, and Structure Therapeutics. AHM is on the Board of Directors of the International Society for the Study of Fatty Acids and Lipids, is a Science Advisor for Benexia and Natures Crops International, and is a co-applicant on a joint government/industry-funded research grant with Natures Crops International.
