Armstrong, Lee A
McFarland, Matthew R https://orcid.org/0009-0004-4308-7545
O’Dea, Rachel
Krutyholowa, Roscislaw https://orcid.org/0000-0002-8200-5627
Gorka, Magdalena
Carroll, Thomas https://orcid.org/0000-0002-0183-7924
Glatt, Sebastian https://orcid.org/0000-0003-2815-7133
Kulathu, Yogesh https://orcid.org/0000-0002-3274-1642
Funding for this research was provided by:
UKRI | Medical Research Council (MC_UU_00018/3)
UKRI | Medical Research Council (MC_UU_00038/3)
EC | Horizon Europe | Excellent Science | HORIZON EUROPE Marie Sklodowska-Curie Actions (765445)
Narodowe Centrum Nauki (2022/47/B/NZ1/01941)
EC | Horizon Europe | Excellent Science | HORIZON EUROPE European Research Council (101002428)
Article History
Received: 15 July 2025
Revised: 11 May 2026
Accepted: 27 May 2026
First Online: 9 June 2026
Disclosure and competing interests statement
: LAA is employed by Outrun Therapeutics, a biotech company focused on the ubiquitin system. The remaining authors declare no competing interests.