Cortez Cardoso Penha, Ricardo https://orcid.org/0000-0002-2847-1993
Sexton Oates, Alexandra
Senkin, Sergey https://orcid.org/0000-0001-5848-005X
Park, Hanla A https://orcid.org/0000-0001-8055-3729
Atkins, Joshua
Holcatova, Ivana
Hornakova, Anna https://orcid.org/0000-0002-1024-8056
Savic, Slavisa https://orcid.org/0000-0002-3635-7437
Ognjanovic, Simona https://orcid.org/0000-0003-3412-2156
Świątkowska, Beata https://orcid.org/0000-0003-3757-3868
Lissowska, Jolanta https://orcid.org/0000-0003-2695-5799
Zaridze, David
Mukeria, Anush
Janout, Vladimir
Chabrier, Amelie
Cahais, Vincent
Cuenin, Cyrille
Scelo, Ghislaine
Foll, Matthieu
Herceg, Zdenko
Brennan, Paul
Smith-Byrne, Karl
Alcala, Nicolas
Mckay, James D https://orcid.org/0000-0002-1787-3874
Funding for this research was provided by:
Cancer Research UK (C98/A24032)
HHS | National Institutes of Health (U01CA155309)
Institut National Du Cancer (GeniLuc2017-1-TABAC-03-CIRC-1-[TABAC17‐022])
Article History
Received: 14 June 2024
Revised: 10 October 2024
Accepted: 21 October 2024
First Online: 26 November 2024
Disclosure and competing interests statement
: The authors declare no competing interests. Where authors are identified as personnel of the International Agency for Research on Cancer/World Health Organization, the authors alone are responsible for the views expressed in this article and they do not necessarily represent the decisions, policies, or views of the International Agency for Research on Cancer/World Health Organization. This study was conducted in accordance with the ethical principles outlined in the Declaration of Helsinki. Informed consent was obtained for all participants included in the discovery and validation sets. Ethical approvals were obtained from Local and Federal Research Ethics Committees, and from the IARC Ethics Committee (IEC Project 17-10A4). For the TCGA datasets, also used as validation set, the enrolling, collection, clinical and genomic data processing and distributions are subject to 45-CFR-46 (the “Common Rule”) governing protection of human research subjects. Under the revised TCGA consent policy, re-consent of still-living participants is no longer a programme-imposed requirement. The Project Team described the best practices for informed consent for participating in TCGA in this memo ( ).