Wright, Sarah N https://orcid.org/0000-0003-3441-5469
Colton, Scott https://orcid.org/0009-0003-6175-0761
Schaffer, Leah V
Pillich, Rudolf T
Churas, Christopher
Pratt, Dexter
Ideker, Trey https://orcid.org/0000-0002-1708-8454
Funding for this research was provided by:
HHS | NIH | National Human Genome Research Institute (U24 HG012107)
HHS | NIH | National Cancer Institute (U24 CA269436)
HHS | NIH | National Institute of General Medical Sciences (P41 GM103504)
HHS | NIH | National Institute on Drug Abuse (P50 DA037844)
Article History
Received: 18 September 2024
Revised: 7 November 2024
Accepted: 11 November 2024
First Online: 9 December 2024
Change Date: 18 August 2025
Change Type: Update
Change Details: In the version of the article initially published in PDF format, symbols in Eq. (1) were rendered incorrectly and are now amended in the HTML and PDF versions of the article.
Disclosure and competing interests statement
: TI is a co-founder, member of the advisory board, and has an equity interest in Data4Cure and Serinus Biosciences. TI is a consultant for and has an equity interest in Ideaya Biosciences. The terms of these arrangements have been reviewed and approved by the University of California San Diego in accordance with its conflict-of-interest policies. TI is a member of the Advisory Editorial Board of The EMBO Journal. This has no bearing on the editorial consideration of this article for publication.