Vu, Duc Tung https://orcid.org/0000-0002-7573-1591
Sibran, William
Metousis, Andreas https://orcid.org/0000-0002-1043-6591
Vandewynckel, Laurine
Eraslan, Basak
Goveas, Liesel https://orcid.org/0000-0003-0925-5870
Itang, Ericka CM https://orcid.org/0000-0003-3387-2537
Deldycke, Claire
Figueroa-Garcia, Adriana https://orcid.org/0000-0002-2913-9589
Lefèbvre, Réginald
Müller-Reif, Johannes Bruno https://orcid.org/0000-0003-3454-2396
Virreira Winter, Sebastian https://orcid.org/0000-0002-2299-8110
Chartier-Harlin, Marie-Christine https://orcid.org/0000-0001-6416-6526
Taymans, Jean-Marc https://orcid.org/0000-0001-5503-5524
Mann, Matthias https://orcid.org/0000-0003-1292-4799
Karayel, Ozge https://orcid.org/0000-0003-2541-1159
Funding for this research was provided by:
The Max Planck Society for the Advancement of Science
The Michael J Fox Foundation (MJFF-12938.4/MJFF-004693)
The Universite de Lille
Article History
Received: 19 March 2025
Revised: 7 January 2026
Accepted: 13 January 2026
First Online: 29 January 2026
Disclosure and competing interests statement
: The authors disclose the following activities and funding sources not directly related to this manuscript: MCCH has served on advisory boards for the European League Against Alzheimer’s Disease (Ligue Européenne contre la maladie d’Alzheimer) and currently serves on the Board of Directors for the Foundation Vaincre Alzheimer and its Scientific Development Committee; these roles involved no financial compensation. J-MT and M-CC-H have received research grants from the Michael J. Fox Foundation, the European Commission, France Parkinson, and the Agence Nationale de la Recherche (ANR). J-MT also received funding from the European Regional Development Fund. MM serves as an editorial advisory board member; this role has no bearing on the editorial consideration of this manuscript. SVW is associated with ions.bio. OK is currently affiliated with Genentech. The remaining authors declare no competing interests.