Xu, Jing https://orcid.org/0009-0000-9978-7111
Mao, Xiao
Liu, Zhen https://orcid.org/0000-0002-9544-4450
Jiang, Na
Wong, Xin E
Liu, Deng https://orcid.org/0009-0001-8409-3608
Wang, Yuan
Zhan, Huaizhe
Liu, Shiyi
Yu, Jiayao
Yuan, Ruiying
Bai, Qingran https://orcid.org/0000-0002-3787-8445
Bai, Xianshu https://orcid.org/0000-0002-4758-1645
Huang, Wenhui
Xie, Ruoxiao https://orcid.org/0009-0000-1000-8960
Krenn, Veronica https://orcid.org/0000-0002-7416-3385
Kirchhoff, Frank https://orcid.org/0000-0002-2324-2761
Wang, Hua
Guo, Zhenming https://orcid.org/0000-0002-6469-414X
Bian, Shan https://orcid.org/0000-0003-4507-3003
Funding for this research was provided by:
National Key R&D Program of China (2021YFA1100400,2020YFA0112500)
National Natural Science Foundation of China (32271019,32300810,12411530079)
China National Postdoctoral Program for Innovative Talents (BX20220230)
Shanghai Sailing Program (22YF1436100)
STCSM | Natural Science Foundation of Shanghai Municipality (22ZR1462600)
Major Scientific and Technological Projects for Collaborative Prevention and Control of Birth Defects in Hunan Province (2023SK4053)
MOE | Fundamental Research Funds for the Central Universities (22120250374)
Peak Disciplines of Institutions of Higher Learning in Shanghai (Type IV)
Human Technopole Early Career Fellowship Programme
Royal Society (IEC\NSFC\233033)
Article History
Received: 28 October 2024
Revised: 11 August 2025
Accepted: 18 August 2025
First Online: 8 September 2025
Disclosure and competing interests statement
: This study has been filed a patent application for use of this disease model in future preclinical investigations.