Schnappinger, Dirk https://orcid.org/0000-0002-4445-7219
Berthel, Steven J https://orcid.org/0000-0003-1250-0208
Boshoff, Helena I M https://orcid.org/0000-0002-4333-206X
Krieger, Inna V
Sukheja, Paridhi
Panda, Saswati https://orcid.org/0000-0003-2057-8822
Rath, Siddhant https://orcid.org/0000-0002-1179-0453
Briggs, Kelsey
Bian, Xuelin https://orcid.org/0000-0002-5315-1203
Rasheed, Sari
Cleghorn, Laura A T
Ghorpade, Sandeep
Lamprecht, Dirk A
Fotouhi, Nader
Müller, Rolf https://orcid.org/0000-0002-1042-5665
Nathan, Carl https://orcid.org/0000-0002-7744-8896
Parish, Tanya
Rhee, Kyu
Warner, Peter https://orcid.org/0009-0006-9374-7024
McNamara, Case W
Rock, Jeremy M https://orcid.org/0000-0002-9310-951X
Sacchettini, James C
Mizrahi, Valerie https://orcid.org/0000-0003-4824-9115
Funding for this research was provided by:
HHS | National Institutes of Health (AI155510)
South African Medical Research Council (N/A)
Global Alliance for TB Drug Development (N/A)
Milstein Program in Chemical Biology and Translational Medicine (N/A)
Bill and Melinda Gates Foundation (INV-055896,INV-055894)
Bill and Melinda Gates Foundation (INV-040484,INV-005757)
Bill and Melinda Gates Foundation (INV-040482)
Bill and Melinda Gates Foundation (INV-047552,INV-07007,INV-083642)
Bill and Melinda Gates Foundation (INV-056399,INV-005585)
Bill and Melinda Gates Foundation (INV-070003)
Bill and Melinda Gates Foundation (INV-044686)
Bill and Melinda Gates Foundation (INV-040487)
Article History
Received: 3 December 2025
Revised: 23 February 2026
Accepted: 6 March 2026
First Online: 7 April 2026
Disclosure and competing interests statement
: The authors declare no competing interests. Dr. Valerie Mizrahi is a member of the EMM Editorial Board. This has no bearing on the editorial consideration of this article for publication.