Mishra, Amrendra
Fanti, Maura
Ge, Xinzhou
Vaughn, Don
Brandhorst, Sebastian
Wei, Min
Hong, Kurt M.
Pellegrini, Matteo
Pijl, Hanno
Houston, Mark C.
Longo, Valter D.
Article History
Received: 17 October 2023
Accepted: 29 October 2023
First Online: 13 December 2023
Change Date: 23 September 2025
Change Type: Correction
Change Details: A Correction to this paper has been published:
Change Details: https://doi.org/10.1038/s44324-025-00084-z
Competing interests
: A grant was provided to the Hypertension Institute in Tennessee by L-Nutra. The Hypertension Institute under the direction of Dr. Mark Houston performed all of the clinical tests in the study. None of the patients were enrolled or studied at USC. The clinical study was sponsored by L-Nutra Inc, which provided the experimental FMD and paid for all the associated procedures and lab tests here presented, making an exception for the PULS test, which was performed at no cost by Predictive Health Diagnostics, 13885 Alton Parkway, Suite B, Irvine CA 92618, United States. The USC-based personnel involved in the study, including the authors of this manuscript, did not receive any compensation from L-Nutra. All the work conducted at USC, data digitalization, as well as the data analysis was verified by an independent statistician at UCLA. This confirmation analysis was funded by a USC chair account under V.D.L. L-Nutra Inc. had no involvement in the study design, collection, analysis, and interpretation of data, writing of the report, manuscript revision or decision to submit the article for publication. V.D.L. who has an equity interest in L-Nutra, did not participate in the collection and analysis of the data. None of the authors that performed data collection or analysis have equity in or are receiving consulting fees from L-Nutra.V.D.L. has equity interest in L-Nutra and owns the patents of the Fasting Mimicking Diet: US 20140227373A1; US 20140112909A1. V.D.L., S.B. and M.W. hold patents related to the Fasting Mimicking Diet but which are not a result of this trial. The University of Southern California has licensed intellectual property to L-Nutra Inc. As part of this license agreement, the University has the potential to receive royalty payments from L-Nutra Inc..