Lacaze, Paul https://orcid.org/0000-0002-0902-6798
Tiller, Jane https://orcid.org/0000-0003-3906-6632
Brotchie, Adam
Nguyen-Dumont, Tu https://orcid.org/0000-0002-6217-0182
Steen, Jason
Belluoccio, Dan
Young, Mary-Anne
Willis, Amanda M. https://orcid.org/0000-0002-1529-3833
Mitchell, Lucas A. https://orcid.org/0000-0001-5160-3299
Terrill, Bronwyn https://orcid.org/0000-0003-0263-363X
Nowak, Kristen J.
Burns, Belinda
Horton, Ari E. https://orcid.org/0000-0003-2043-4343
Nicholls, Stephen J.
Ademi, Zanfina
Green, Robert C. https://orcid.org/0000-0001-8472-0424
Manchanda, Ranjit https://orcid.org/0000-0003-3381-5057
Thompson, Bryony A.
Thomas, David
Milne, Roger L. https://orcid.org/0000-0001-5764-7268
Bruinsma, Fiona
Delatycki, Martin B.
Pang, Jing https://orcid.org/0000-0002-9700-6948
Watts, Gerald F. https://orcid.org/0000-0003-2276-1524
Macrae, Finlay
Poplawski, Nicola https://orcid.org/0000-0002-9372-3325
Kirk, Judy
Tucker, Kathy https://orcid.org/0000-0002-7180-6576
Andrews, Lesley
Wallis, Mathew https://orcid.org/0000-0002-5441-1732
Susman, Rachel
Pachter, Nicholas https://orcid.org/0000-0002-8144-1363
Sullivan, David
Ragunathan, Abiramy
James, Paul https://orcid.org/0000-0002-4361-4657
Zalcberg, John https://orcid.org/0000-0002-6624-0782
McNeil, John J. https://orcid.org/0000-0002-1049-5129
Southey, Melissa C.
Winship, Ingrid
Funding for this research was provided by:
Department of Health | National Health and Medical Research Council (2026325)
Department of Health | National Health and Medical Research Council (GNT2017325)
National Heart Foundation of Australia (102604)
Victoria Cancer Agency MCRF21029
Article History
Received: 3 August 2025
Accepted: 10 November 2025
First Online: 15 January 2026
Competing interests
: R.M. declares advisory board membership from Astrazeneca/MSD/EGL/GSK, and research funding from Yorkshire Cancer research, CRUK and Rosetrees trust outside this study. R.C.G. has received compensation for advising Allelica, Atria, Fabric, Genomic Life and Jupiter Genomics; and is a co-founder of Genome Medical and Nurture Genomics. S.N. has received research support from AstraZeneca, Amgen, Anthera, CSL Behring, Cerenis, Eli Lilly, Esperion, Resverlogix, Novartis, InfraReDx and Sanofi-Regeneron and is a consultant for Amgen, Akcea, AstraZeneca, Boehringer Ingelheim, CSL Behring, Eli Lilly, Esperion, Kowa, Merck, Takeda, Pfizer, Sanofi-Regeneron and Novo Nordisk. The other authors declare no competing interests.