Text and Data Mining valid from 2017-02-01
Received: 16 December 2016
Accepted: 5 January 2017
First Online: 24 February 2017
: ECP, JD, RC, XZ, DC, RH, TD, MZ, BS, PF, MR, FS, EK, HJM, SF, RS, JAN and RMA are employees of Janssen Research and Development, L.L.C. The remaining authors declare no conflict of interest.