Volpicelli-Daley, Laura A
Luk, Kelvin C
Lee, Virginia M-Y
Article History
First Online: 14 August 2014
Change Date: 1 September 2016
Change Type: Update
Change Details: Since the publication of this protocol, the safe handling procedures for α-synuclein fibrils have been updated (ref. 1). 1% SDS (wt/vol) should be used to inactivate α-synuclein fibrils in place of NaOH, which does not appear to work. We also recommend performing the sonication step in a biosafety level 2 hood. Please see ref. 1 for further information on the safe handling of fibrils. 1. Bousset, L. <i>et al</i>. An efficient procedure for removal and inactivation of alpha-synuclein assemblies from laboratory materials. <i>J. Parkinsons Dis</i>. <b>6</b>, 143–151 (2016).
Competing interests
: The authors declare no competing financial interests.