Kortüm, Benedikt http://orcid.org/0000-0003-3734-6665
Radhakrishnan, Harikrishnan
Zincke, Fabian
Sachse, Christoph
Burock, Susen
Keilholz, Ulrich
Dahlmann, Mathias
Walther, Wolfgang
Dittmar, Gunnar http://orcid.org/0000-0003-3647-8623
Kobelt, Dennis http://orcid.org/0000-0002-9373-0648
Stein, Ulrike http://orcid.org/0000-0001-7006-282X
Funding for this research was provided by:
Charité – Universitätsmedizin Berlin
Deutsches Krebsforschungszentrum
BIH Innovations & SPARK-BIH Validation Fund
Berlin School of Integrative Oncology BSIO
Article History
Received: 19 December 2021
Revised: 30 June 2022
Accepted: 1 July 2022
First Online: 25 August 2022
Competing interests
: All experiments were carried out in accordance with the guidelines approved by the institutional review board, number AA3/03/45, of the Charité—Universitätsmedizin Berlin, Germany. All patients gave written informed consent and the authors complied with all relevant ethical regulations for research involving human participants. For all studies, the welfare of the animals was maintained in accordance with the general principles governing the use of animals in experiments of the European Communities and German legislation. The study was performed in accordance to the United Kingdom Coordinating Committee on Cancer Research (UKCCCR) regulations for the Welfare of Animals and of the German Animal Protection Law and approved by the local responsible authorities, Berlin, Germany (State Office of Health and Social Affairs, Berlin, Germany), REG0010/19, G0333/18.CS works for NMI TT Pharmaservices, who offer DigiWest as a service. BK, HR, FB, SB, UK, MD, WW, GD, DK, and US declare no competing interests.
: All experiments were carried out in accordance with the guidelines approved by the institutional review board, number AA3/03/45, of the Charité—Universitätsmedizin Berlin, Germany. All patients gave written informed consent and the authors complied with all relevant ethical regulations for research involving human participants. For all studies, the welfare of the animals was maintained in accordance with the general principles governing the use of animals in experiments of the European Communities and German legislation. The study was performed in accordance to the United Kingdom Coordinating Committee on Cancer Research (UKCCCR) regulations for the Welfare of Animals and of the German Animal Protection Law and approved by the local responsible authorities, Berlin, Germany (State Office of Health and Social Affairs, Berlin, Germany), REG0010/19, G0333/18.