Sartor, Oliver
Armstrong, Andrew J. http://orcid.org/0000-0001-7012-1754
Ahaghotu, Chiledum
McLeod, David G.
Cooperberg, Matthew R. http://orcid.org/0000-0003-4339-6685
Penson, David F.
Kantoff, Philip W.
Vogelzang, Nicholas J.
Hussain, Arif
Pieczonka, Christopher M.
Shore, Neal D.
Quinn, David I.
Small, Eric J.
Heath, Elisabeth I.
Tutrone, Ronald F.
Schellhammer, Paul F.
Harmon, Matthew
Chang, Nancy N.
Sheikh, Nadeem A.
Brown, Bruce
Freedland, Stephen J.
Higano, Celestia S.
Funding for this research was provided by:
Dendreon Pharmaceuticals, LLC
Article History
Received: 30 October 2019
Revised: 29 January 2020
Accepted: 11 February 2020
First Online: 28 February 2020
Compliance with ethical standards
:
: OS served as a consultant for and received personal fees from Advanced Accelerator Applications, Astellas, AstraZeneca, Bavarian-Nordic, Bayer, Bellicum, Blue Earth Diagnostics, BMS, Constellation, Dendreon, EMD Serono, Jenssen, Myriad, Myovant, Noxopharm, Pfizer, Progenics, and Sanofi. Dr. Sartor has also received grants from AstraZeneca, Bayer, Dendreon, Endocyte, Innocrin, Invitae, Jenssen, Merck, NCI, NRG, Sanofi, and Sotio. He is co-chairman of the GU Committee for NRG and a consultant on the board of scientific counselors for NCI. AJA has received grants and personal fees from Dendreon, serving as consultant/advisor, researcher, and speaker. Outside of the submitted work, Dr. Armstrong received grants, personal fees and other support from Bayer as consultant/advisor, researcher, and speaker. Dr. Armstrong received personal fees and other support as honoraria, consultant/advisor, and travel expenses. He also served as a consultant/advisor to Merck, Astra Zeneca, Janssen, and Pfizer/Astellas. His institution Duke received research funding from Bayer, Novartis, Janssen, Gilead Sciences, Roche/Genentech, Bristol-Myers-Squibb, Constellation, Merck, Astra Zeneca, Janssen, and Pfizer/Astellas. CA has nothing to disclose. DGM has nothing to disclose. MRC has received personal fees from Dendreon related to the PROCEED trial steering committee, and served in an advisory or consultancy role for Bayer, Abbvie, and Astra Zeneca. Dr. Cooperberg has also participated in a registry steering committee for Astella. DFP has nothing to declare. PWK has received personal fees from BIND Biosciences, Bavarian Nordic Immunotherapies, DRGT, Janssen, Merck, Metamark, OncoCellMDX, Sanofi, Tarveda Pharmaceuticals, Thermo Fisher, GE Healthcare, Context Therapeutics, New England Research Institutes, SEER Biosciences and Placon. Dr. Kantoff also has investment interests in DRGT, Tarveda Pharmaceuticals, Context Therapeutics, SEER Biosciences and Placon. He is also a board member for Context Therapeutics. NJV has nothing to disclose. AH has nothing to disclose. CMP has received research grants from Dendreon, Bayer, Astellas, Pfizer, LUGPA, Janssen, Astra Zeneca, and Veru. No other relationships present a potential conflict of interest. NDS has nothing to declare. DIQ received research grant/funding from Seattle Genetics, MSD, Novartis, acted as an advisor/consultant for Astellas, Astra Zeneca, Bayer, BMS, Dendreon, Exelixis, Roche, Janssen, MSD, Novartis, Pfizer, Sanofi, and received travel, accommodation and expenses from Pfizer, MSD, Astra Zeneca, BMS, Roche. EJS has received honoraria from Janssen and has served as a consultant or advisory board member for Janssen, Fortis, Beigene, and Tolero. He owns stock in Fortis Therapeutics and Harpoon Therapeutics. EIH received research funding and honoraria, and has served as a consultant for Dendreon. Dr. Heath has also received personal fees and/or non-financial support from Bayer, Sanofi, Seattle Genetics, and Agensys. She received research funding from Tokai Pharmaceuticals, Seattle Genetics, Agensys, Dendreon, Genentech/Roche, Millenium, Caris Life Sciences, Boehringer Ingelheim, Merck Sharp & Dohme, Plexxicon, Corcept Therapeutics, Fortis, Astellas Pharma, Medivation, AstraZeneca, Ignyta, Synta, Esanik, Zenith Epigenetics, Oncolys BioPharma, Curemeta, BMS, eFFECTOR Therapeutics, Celldex, Inovio Pharmaceuticals, Celgene, and Merck. RFT has nothing to disclose. PFS has nothing to disclose. MH is a full-time employee of Dendreon. NNC was a full-time employee of Dendreon at the time of the analyses and initial drafting of this manuscript. NAS is a full-time employee of Dendreon. BB is a full-time employee of Dendreon. SJF has received personal fees from Dendreon. CSH reports no conflicts of interest related to the work under consideration. Outside of the submitted work, Dr. Higano has participated in sponsored research with Aptevo, Aragon Pharma, Astellas, AstraZeneca, Bayer, Clovis, Dendreon, eFFECTOR Therapeutics, Emergent, Ferring, Genentech, Hoffman-LaRoche, Medivation, and Pfizer. Dr. Higano also has received personal fees for advisory board participation from Aptevo, Asana, Astellas, Bayer, Blue Earth Diagnostics, Churchill Pharma, Clovis Oncology, Dendreon, Endocyte, Ferring, Hinova, Janssen, Myriad, Orion, and Pfizer.