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Karunamuni, Roshan
Fan, Chun Chieh http://orcid.org/0000-0001-9437-2128
Asona, Lui http://orcid.org/0000-0002-0076-3492
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Cybulski, Cezary
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Menegaux, Florence http://orcid.org/0000-0003-3363-6411
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Hamilton, Robert J.
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Kaneva, Radka
Logothetis, Christopher J.
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Castelao, Jose Esteban
Townsend, Paul A.
Crawford, Dana C. http://orcid.org/0000-0002-6437-6248
Petrovics, Gyorgy http://orcid.org/0000-0003-3732-284X
van Schaik, Ron H. N.
Parent, Marie-Élise http://orcid.org/0000-0002-4196-3773
Hu, Jennifer J.
Zheng, Wei http://orcid.org/0000-0003-1226-070X
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Article History
Received: 21 September 2021
Accepted: 12 January 2022
First Online: 12 February 2022
Competing interests
: All authors declare no support from any organization for the submitted work except as follows: AMD and TMS report a past research grant from the US Department of Defense. OAA reports research grants from K.G Jebsen Stiftelsen, Research Council of Norway, and South East Norway Health Authority. Authors declare no financial relationships with any organizations that might have an interest in the submitted work in the previous 3 years except as follows, with all of these relationships outside the present study: TMS reports honoraria from Multimodal Imaging Services Corporation, Varian Medical Systems, and WebMD; he has an equity interest in CorTechs Labs and also serves on its Scientific Advisory Board. These companies might potentially benefit from the research results. The terms of this arrangement have been reviewed and approved by the University of California San Diego in accordance with its conflict-of-interest policies. OAA reports speaker honoraria from Lundbeck. Authors declare no other relationships or activities that could appear to have influenced the submitted work except as follows: OAA has a patent application # U. S. 20150356243 pending; AMD also applied for this patent application and assigned it to UC San Diego. AMD has additional disclosures outside the present work: founder, equity holder, and advisory board member for CorTechs Labs, Inc.; founder and equity holder in HealthLytix, Inc., advisory board member of Human Longevity, Inc.; recipient of nonfinancial research support from General Electric Healthcare. OAA is a consultant for HealthLytix, Inc. Additional acknowledgments for the PRACTICAL consortium and contributing studies are described in the Supplementary Information.
: The present analyses used de-identified data from the PRACTICAL consortium and have been approved by the Institutional Review Board at the University of California San Diego. All contributing studies were approved by the relevant ethics committees and performed in accordance with the Declaration of Helsinki.