Gollins, Simon
West, Nicholas
Sebag-Montefiore, David
Susnerwala, Shabbir
Falk, Stephen
Brown, Nick
Saunders, Mark
Quirke, Philip
Ray, Ruby
Parsons, Philip
Griffiths, Gareth
Maughan, Tim
Adams, Richard
Hurt, Chris http://orcid.org/0000-0003-1206-8355
Funding for this research was provided by:
Cancer Research UK (CRUK) (C23134/A11537, C23134/A11537, C23134/A11537, C23134/A11537, C23134/A11537, C23134/A11537, C23134/A11537, C23134/A11537, C23134/A11537, C23134/A11537, C23134/A11537, C23134/A11537, C23134/A11537, C23134/A11537)
Article History
Received: 25 March 2018
Revised: 30 June 2018
Accepted: 9 July 2018
First Online: 17 August 2018
Competing interests
: Outside of the submitted work S.G. has received research funding from Roche and Pfizer. N.W. reports grants from Yorkshire Cancer Research, grants from Pathological Society of Great Britain and Ireland, during the conduct of the study; grants from Academy of Medical Sciences, grants from Cancer Research UK, outside the submitted work. N.B. reports speaking fees from Pfizer, and travel/accommodation support from Roche. P.Q. reports personal fees and research funding from Amgen, personal fees and research funding from Roche, research funding from Ventana, during the conduct of the study; grants from Yorkshire Cancer Research programme grant, within and outside the submitted work and grants from Cancer Research UK, outside the submitted work. R.A. has received research funding from Cancer Research UK, personal fees and travel from Merck Serono, Amgen and Servier.
: The trial protocol, EudraCT No.: 2010-023083-40, was approved by the UK Medicines and Healthcare products Regulatory Agency and a UK Multi-Centre Research Ethics Committee (12/WA/0051), sponsored by Cardiff University and coordinated by the Centre for Trials Research at Cardiff University. All patients provided written informed consent before inclusion. The study was performed in accordance with the Declaration of Helsinki.
: All authors gave final approval of the version to be published.
: Funded by Cancer Research UK (ref. C23134/A11537).