Ijsselsteijn, Marieke Erica
Petitprez, Florent
Lacroix, Laetitia
Ruano, Dina
van der Breggen, Ruud
Julie, Catherine
Morreau, Hans
Sautès-Fridman, Catherine
Fridman, Wolf Herman
de Miranda, Noel Filipe da Cunha Carvalho
Funding for this research was provided by:
American Association for Cancer Research (15-40-1645-DEMI, 15-40-1645-DEMI)
KWF Kankerbestrijding (UL 2015-7664, UL 2015-7664)
SIRIC CARPEM
ZonMw (016.176.144, 016.176.144)
Institut National Du Cancer (C1608DS)
Article History
Received: 5 September 2018
Revised: 6 February 2019
Accepted: 18 February 2019
First Online: 13 March 2019
Competing interests
: The authors declare no competing interests.
: Data is available upon request.
: This study was approved by the Medical Ethical Committee of the Leiden University Medical Center (protocol P15.282) and of the Ambroise Paré Hospital (protocol Reincolon). Patient samples were anonymised and handled according to the medical ethical guidelines described in the Code of Conduct for Proper Secondary Use of Human Tissue of the Dutch Federation of Biomedical Scientific Societies. This research was conducted according to the recommendations outlined in the Helsinki declaration.
: The authors acknowledge funding from the Fight Colorectal Cancer-Michael’s Mission-AACR Fellowship in Young Onset, Late-Stage Colorectal Cancer Research 2015, the KWF Bas Mulder Award UL 2015-7664, the ZonMw Veni grant (016.176.l44), the Institut National de la Santé et de la Recherche Médicale, the University Paris Descartes, the Sorbonne University, and the SIRIC CARPEM (“Cancer research for personalised medicine”), the Labex Immuno-Oncology Excellence and Institut du Cancer (INCa) HTE Plan Cancer (C1608DS) Programs. F.P. was supported by CARPEM doctorate fellowship.