Hänninen, Ulrika A.
Wirta, Erkki-Ville
Katainen, Riku
Tanskanen, Tomas
Hamberg, Jiri
Taipale, Minna
Böhm, Jan
Renkonen-Sinisalo, Laura
Lepistö, Anna
Forsström, Linda M.
Pitkänen, Esa
Palin, Kimmo
Seppälä, Toni T.
Mäkinen, Netta
Mecklin, Jukka-Pekka
Aaltonen, Lauri A.
Funding for this research was provided by:
The Ida Montin Foundation, The Juhani Aho Foundation for Medical Research
Academy of Finland (250345, 312041)
The Finnish Cancer Society, The Sigrid Juselius Foundation, The Jane and Aatos Erkko Foundation
Article History
Received: 25 October 2018
Revised: 26 February 2019
Accepted: 1 March 2019
First Online: 21 March 2019
Competing interests
: L.A.A. has received a lecturing fee from Roche Oy and Bayer Oy. T.T.S. reports non-financial support from Medtronic Finland Oy, outside the submitted work. Other authors declare no competing interests.
: Somatic sequence data generated and analysed during the current study have been deposited at the European Genome-phenome Archive (EGA), which is hosted by the EBI and the CRG, under study accession number (EGAS00001003474). Further information about EGA can be found onExternalRef removed“The European Genome-phenome Archive of human data consented for biomedical research” (ExternalRef removed). Data are available on request upon publication from the EGA database by contacting the data access committee (DAC accession EGAC00001000649, dac-tumorgenomics@helsinki.fi) assigned for this project. Data are restricted due to reasons of patient confidentiality.
: The study has been reviewed and approved by the Ethics Committee of the Hospital District of Helsinki and Uusimaa, Finland (408/13/03/03/2009). Either a signed informed consent or authorisation from the National Supervisory for Welfare and Health was obtained for all the samples. This study has been conducted according to the Declaration of Helsinki.
: This work is published under the standard license to publish agreement. After 12 months the work will become freely available and the license terms will switch to a Creative Commons Attribution 4.0 International (CC BY 4.0).