Brzezinski, Jack
Choufani, Sanaa
Romao, Rodrigo
Shuman, Cheryl
Chen, Haiying
Cunanan, Joanna
Bagli, Darius
Grant, Ronald
Lorenzo, Armando
Weksberg, Rosanna http://orcid.org/0000-0002-6501-4150
Article History
Received: 4 April 2020
Revised: 7 August 2020
Accepted: 9 September 2020
First Online: 5 October 2020
Ethics approval and consent to participate
: Institutional ethics approval was obtained through the Hospital for Sick Children Research Ethics Board (#1000038847 and #019880564) and this study was performed in accordance with the Declaration of Helsinki. Informed written consent was provided by each participant.
: Raw DNA methylation data will be available at the Gene Expression Omnibus. Variants identified in tumour samples will be uploaded to the COSMIC database. Aligned BAM files and variant call files will be available upon request. All bioinformatics analyses were done in the R environment utilising packages freely available from the CRAN network or Bioconductor.org. Scripts written utilising these packages will be available without restriction upon request.
: The authors declare no competing interests.
: This study was supported by grants from the C17 Canadian Childhood Cancer network (1000039113) and from the Sick Kids Foundation (9535144613).