Zhang, Xiaomeng
Theodoratou, Evropi
Li, Xue
Farrington, Susan M.
Law, Philip J.
Broderick, Peter
Walker, Marion
Klimentidis, Yann C.
Rees, Jessica M. B.
Houlston, Richard S.
Tomlinson, Ian P. M.
Burgess, Stephen http://orcid.org/0000-0001-5365-8760
Campbell, Harry
Dunlop, Malcolm G. http://orcid.org/0000-0002-3033-5851
Timofeeva, Maria http://orcid.org/0000-0002-2503-4253
Article History
Received: 4 August 2020
Revised: 20 November 2020
Accepted: 8 December 2020
First Online: 29 January 2021
Ethics approval and consent to participate
: All included datasets were approved by respective ethics/institutional review committees, in accordance with the Declaration of Helsinki. The details were described in Law et al.<sup>14</sup>.
: Not applicable.
: Availability of colorectal cancer GWASs was described by Law et al.<sup>14</sup> (PMID 31089142). Availability of self-reported habitual physical activity GWAS was described by Klimentidis et al.<sup>15</sup> (PMID 29899525). The summary-level data from the average acceleration vector magnitude GWAS was available at Doherty et al.<sup>16</sup> (PMID 30531941). The summary-level data for GWAS on BMI, body fat percentage, waist circumference and body fat distribution were extracted from Locke et al.<sup>60</sup> (PMID 25673413), Bycroft et al.<sup>61</sup> (PMID 30305743), Shungin et al.<sup>62</sup> (PMID 25673412) and Ralk-Andersen et al.<sup>11</sup> (PMID 30664634), respectively. All data generated during this study are included in this published article and its supplementary information files.
: The authors declare no competing interests.
: This work was supported by Cancer Research UK programme grant [grant number C348/A18927]; Cancer Research UK [grant number C1298/A25514]; National Cancer Research Network; Cancer Research UK Career Development Fellowship [grant number C31250/A22804]; The Darwin Trust of Edinburgh; National Institute of Health [grant number R01 HL136528].