Conlon, Neil T. http://orcid.org/0000-0001-5921-7114
Kooijman, Jeffrey J.
van Gerwen, Suzanne J. C.
Mulder, Winfried R.
Zaman, Guido J. R.
Diala, Irmina
Eli, Lisa D.
Lalani, Alshad S.
Crown, John
Collins, Denis M.
Funding for this research was provided by:
Irish Research Council (EPSPD/2020/24, EPSD/2020/24)
Cancer Clinical Research Trust (Charity no. CHY12210) Puma Biotechnology Inc
Cancer Clinical Research Trust (Charity no. CHY12210) Puma Biotechnology Inc.
Article History
Received: 7 August 2020
Revised: 9 December 2020
Accepted: 17 December 2020
First Online: 21 January 2021
Ethics approval and consent to participate
: All cancer cell lines were purchased from the American Type Culture Collection (ATCC) (Manassas, VA), except II-18, which was acquired from RIKEN BioResource Research Center (Tsukuba, Ibaraki, Japan), and HEC-1, HEC-6, and HEC-251, which were purchased from Japanese Collection of Research Bioresources Cell Bank (JCRB) (Ibaraki city, Osaka, Japan).
: Not applicable.
: The sensitivity data in this study are included in the manuscript as Supplementary Table InternalRef removed. Genomic and gene expression data used in this study were gathered from publicly available databases, as described in ‘Methods’.
: D.M.C., N.T.C., and J.C. have received academic research funding from Puma Biotechnology Inc. D.M.C. has received consultancy fees from Puma Biotechnology Inc. J.C. has been on advisory boards for Puma Biotechnology Inc., Seattle Genetics, and Novartis Ireland. G.J.R.Z. is managing director and shareholder of Netherlands Translational Research Center B.V. (NTRC). S.J.C.v.G., J.J.K., and W.R.M. are employees of NTRC. I.D., L.D.E., and A.S.L. are employees and shareholders in Puma Biotechnology Inc.
: The work undertaken by NTRC was funded by Puma Biotechnology Inc. N.T.C. was funded through an Irish Research Council Enterprise Partnership Fellowship (EPSPD/2020/24) with Cancer Clinical Research Trust (Charity No. CHY12210). D.M.C. was funded by The Caroline Foundation and the Cancer Clinical Research Trust.