Received: 26 July 2019
Revised: 7 April 2020
Accepted: 15 April 2020
First Online: 8 May 2020
Ethics approval and consent to participate
: The study was approved by Regional Committee on Health Research Ethics (The Capital Region of Denmark), approval number H-16049387. All patients provided informed consent to participate in the study, and the study was conducted accordance with the Declaration of Helsinki.
: Not applicable.
: The data set used and analysed during the current study is available from the corresponding author on reasonable request.
: The authors declare no competing interests.
: This project received funding from the Research Foundation of Rigshospitalet, the Danish Cancer Society (grant nos. R167-A10858 and R134-A8543-B79), the Aase and Ejnar foundation, National Cancer Institute (NCI grant no. P30 CA 134274-04) the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (grant agreement no. 670261), the Lundbeck Foundation, the Novo Nordisk Foundation, the Innovation Fund Denmark, Svend Andersen Foundation, the Neye Foundation. SMB acknowledges support from the Maryland Department of Health’s Cigarette Restitution Fund Program and the NCI University of Maryland Cancer Center Support Grant (P30CA134274).