Received: 17 February 2020
Revised: 2 May 2020
Accepted: 13 May 2020
First Online: 16 June 2020
Ethics approval and consent to participate
: Not applicable. The PIONeeR study is registered as NCT03493581.
: Not applicable.
: The authors declare no competing interests.
: PIONeeR is supported by the French National Research Agency (grant# ANR-17-RHUS-0007), and is a partnership between AMU, APHM, AstraZeneca, Centre Léon Bérard, CNRS, HalioDx, ImCheck Therapeutics, Innate Pharma, Inserm and Institut Paoli Calmettes with an APHM sponsoring. QUANTIC is funded by ITMO Cancer AVIESAN and French Institut National du Cancer (grant #19CM148-00).