Amadou, Amina
Freisling, Heinz http://orcid.org/0000-0001-8648-4998
Jenab, Mazda
Tsilidis, Konstantinos K.
Trichopoulou, Antonia
Boffetta, Paolo
Van Guelpen, Bethany
Mokoroa, Olatz
Wilsgaard, Tom
Kee, Frank
Schöttker, Ben http://orcid.org/0000-0002-1217-4521
Ordóñez-Mena, José M.
Männistö, Satu
Söderberg, Stefan
Vermeulen, Roel C. H.
Quirós, J. Ramón
Liao, Linda M.
Sinha, Rashmi
Kuulasmaa, Kari http://orcid.org/0000-0003-2165-1411
Brenner, Hermann
Romieu, Isabelle
Funding for this research was provided by:
World Cancer Research Fund (IIG_2019_1978)
Article History
Received: 27 July 2020
Revised: 28 February 2021
Accepted: 4 March 2021
First Online: 26 March 2021
Ethics approval and consent to participate
: All studies participating in CHANCES were conducted in accordance with the Declaration of Helsinki. For each study, investigators satisfied the local requirements for ethical research, including obtaining informed consent from participants.
: Not applicable.
: The CHANCES participating cohorts’ data are available only to the collaborating scientists from the respective CHANCES participating centres. The data may be available upon request for some of the participating centres but not for all due to relevant data protection laws.
: The authors declare no competing interests.
: Data used throughout the present study are derived from the CHANCES project. The project is coordinated by the Hellenic Health Foundation, Greece. The project received funding by the FP7 framework programme of DG-RESEARCH in the European Commission (grant agreement no. HEALTH-F3-2010-242244). EPIC Greece: funded by the Hellenic Health Foundation. EPIC Netherlands: funded by European Commission (DG SANCO), Dutch Ministry of Public Health, Welfare and Sports (VWS), The National Institute for Public Health and the Environment, the Dutch Cancer Society, the Netherlands Organisation for Health Research and Development (ZONMW) and World Cancer Research Fund (WCRF). EPIC Spain: supported by Health Research Fund (FIS) of the Spanish Ministry of Health RTICC ‘Red Temática de Investigación Cooperativa en Cáncer (grant numbers: Rd06/0020/0091 and Rd12/0036/0018), Regional Governments of Andalucía, Asturias, Basque Country, Murcia (project 6236) and Navarra, Instituto de Salud Carlos III, Redes de Investigacion Cooperativa (RD06/0020). EPIC Umea: funded by Region Västerbotten and the Swedish Research Council. ESTHER: funded by the Baden-Württemberg State Ministry of Science, Research and Arts (Stuttgart, Germany), the Federal Ministry of Education and Research (Berlin, Germany) and the Federal Ministry of Family Affairs, Senior Citizens, Women and Youth (Berlin, Germany). Data from FINRISK, Belfast and Northern Sweden were harmonised for this analysis in the MOnica Risk, Genetics, Archiving and Monograph (MORGAM) Project. The activities of the MORGAM Data Centre have been sustained also by recent funding from European Union FP7 project BiomarCaRE (HEALTH-F2-2011-278913). PRIME Belfast: supported by grants from the Institut National de la Santé et de la Recherche Médicale (INSERM), the Merck, Sharp & Dohme-Chibret Laboratory and the Northern Ireland Health & Social Care Research and Development Office. Northern Sweden MONICA Study: funded by Umeå University and the county councils of Norr and Västertbotten. Tromsø: funded by UiT The Arctic University of Norway, the National Screening Service and the Research Council of Norway. This study was in part funded by the World Cancer Research Fund (WCRF UK) as part of the World Cancer Research Fund International grant programme (IIG_2019_1978, Principal Investigator, Heinz Freisling).