Sjoberg, Hanna T.
Philippou, Yiannis
Magnussen, Anette L.
Tullis, Iain D. C.
Bridges, Esther
Chatrian, Andrea
Lefebvre, Joel
Tam, Ka Ho
Murphy, Emma A.
Rittscher, Jens
Preise, Dina
Agemy, Lilach
Yechezkel, Tamar
Smart, Sean C.
Kinchesh, Paul
Gilchrist, Stuart
Allen, Danny P.
Scheiblin, David A. http://orcid.org/0000-0002-5505-2540
Lockett, Stephen J.
Wink, David A.
Lamb, Alastair D. http://orcid.org/0000-0002-2968-7155
Mills, Ian G. http://orcid.org/0000-0001-5347-5083
Harris, Adrian http://orcid.org/0000-0003-1376-8409
Muschel, Ruth J.
Vojnovic, Boris
Scherz, Avigdor
Hamdy, Freddie C.
Bryant, Richard J. http://orcid.org/0000-0002-8330-9251
Article History
Received: 30 November 2020
Revised: 29 April 2021
Accepted: 25 May 2021
First Online: 21 June 2021
Ethics approval and consent to participate
: No patient-derived material was used in this study and thus there is no patient-specific ethical approval to report. Animal procedures were in accordance with UK Animal law (Scientific Procedures Act 1986), including local ethics committee (Clinical Medicine Old Road Campus Animal Welfare Ethical Review Body, University of Oxford) and UK Government Home Office approval. TRAMP-C1 (ATCC<sup>®</sup> CRL-2730™) and MyC-CaP (ATCC® CRL-3255™) cell lines were purchased from American Type Culture Collection (ATCC<sup>®</sup>).
: Not applicable.
: The authors agree to make the data in this paper publically available upon request where possible.
: A.S. is the inventor of TOOKAD VTP and entitled to royalties through Yeda, the commercial branch of the Weizmann Institute of Science, Rehovot, Israel. J.R. is a co-founder of Ground Truth Labs, Oxford, UK. All other authors have no potential conflicts of interest to declare, and this academic study was performed independent of commercial involvement.
: This work was funded by a Cancer Research UK/Royal College of Surgeons of England Clinician Scientist Fellowship (reference C39297/A22748, for R.J.B. and H.S.), and by a research grant from The Urology Foundation (for Y.P.), along with a Cancer Research UK Clinical Research Training Fellowship (for Y.P.). B.V. and I.D.C.T. were funded by a Cancer Research UK program grant (C5255/A12678). J.L. was supported by a FRQNT postdoctoral scholarship (reference 257844). A.M. was funded by the John Fell Fund and the John Black Charitable Foundation. The authors also acknowledge Federal funds from the National Cancer Institute, National Institutes of Health, under Contract No. 75N91019D00024. The content of this publication does neither necessarily reflect the views or policies of the Department of Health and Human Services nor does mention of trade names, commercial products or organisations imply endorsement by the U.S. Government.