Woll, Penella J.
Gaunt, Piers
Gaskell, Charlotte
Young, Robin http://orcid.org/0000-0002-5146-9074
Benson, Charlotte
Judson, Ian R.
Seddon, Beatrice M.
Marples, Maria
Ali, Nasim
Strauss, Sandra J.
Lee, Alexander http://orcid.org/0000-0003-2976-6811
Hughes, Ana
Kaur, Baljit
Hughes, David
Billingham, Lucinda
Funding for this research was provided by:
Cancer Research UK (CR UK 09/009)
Pfizer Inc. | Pfizer UK (n/a)
Article History
Received: 26 January 2023
Revised: 3 August 2023
Accepted: 23 August 2023
First Online: 8 September 2023
Competing interests
: The authors declare no competing interests.
: The trial was sponsored by Sheffield Teaching Hospitals NHS Foundation Trust and run by the Cancer Research UK Clinical Trials Unit, University of Birmingham. The protocol and subsequent amendments were approved by the West Midlands–Edgbaston Research Ethics Committee (09/H1208/42) and local institutional review boards in accordance with the ethical principles of the Declaration of Helsinki and Good Clinical Practice Guidelines. Signed informed consent was obtained from all patients before registration. Oversight of the trial was provided by the independent Data Monitoring Committee.