Karsten, Stella http://orcid.org/0000-0001-6191-4314
Fiskesund, Roland
Zhang, Xing-Mei
Marttila, Petra http://orcid.org/0000-0002-0115-8067
Sanjiv, Kumar
Pham, Therese
Rasti, Azita
Bräutigam, Lars
Almlöf, Ingrid
Marcusson-Ståhl, Maritha
Sandman, Carolina
Platzack, Björn
Harris, Robert A.
Kalderén, Christina
Cederbrant, Karin
Helleday, Thomas http://orcid.org/0000-0002-7384-092X
Warpman Berglund, Ulrika
Article History
First Online: 27 August 2021
Competing interests
: A patent has been filed with data generated in this manuscript, where TH is listed as one of the inventors. The patent is fully owned by a non-profit public foundation, the Helleday Foundation for medical research (THF), and TH and UWB are members of THF board. Oxcia AB has license to the patent and perform clinical development of TH1579. UWB is CEO of Oxcia AB, TH is board member of Oxcia AB. The other authors declare no conflict of interest.
: This study was performed in accordance with the Declaration of Helsinki. The in vitro experiments on human T cells were performed on products from buffy coats extracted from blood products donated by healthy donors for the blood banks of the Karolinska University Hospital (Stockholm, Sweden), where no additional intervention was performed on the donors specifically for this research. There was no possibility to trace back the samples to the donors. The in vivo studies were approved by the local ethical committees (Stockholm North, number N138/14 for the EAE study; Stockholm South, number S7-15 for the TDAR study).