Kim, Ki-Ryeong
Cho, Eun-Jung
Eom, Jae-Won
Oh, Sang-Seok
Nakamura, Tomohiro http://orcid.org/0000-0002-4246-7771
Oh, Chang-ki
Lipton, Stuart A. http://orcid.org/0000-0002-3490-1259
Kim, Yang-Hee http://orcid.org/0000-0002-0595-8547
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Institute on Aging (R01 AG061845, RF1 AG057409, R01 AG056259, R35 AG071734)
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (RF1 NS123298, R61 NS122098, R01 NS086890)
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke
U.S. Department of Health & Human Services | NIH | National Institute on Drug Abuse (R01 DA048882, DP1 DA041722)
U.S. Department of Health & Human Services | NIH | National Institute on Drug Abuse
U.S. Department of Health & Human Services | NIH | National Institute on Aging
U.S. Department of Health & Human Services | NIH | National Institute on Aging
U.S. Department of Health & Human Services | NIH | National Institute on Aging
National Research Foundation of Korea (NRF-2017M3C7A1028945, NRF-2018R1D1A1B07049746, NRF-2021R1A2C2008234)
Article History
Received: 17 May 2021
Revised: 1 April 2022
Accepted: 8 April 2022
First Online: 24 April 2022
Competing interests
: The authors declare that YHK is a shareholder of Zincure Corp., and that KRK is currently employed by Zincure Corp. SAL is a scientific founder of Adamas Pharmaceuticals, Inc., EuMentis Therapeutics, Inc., and Infla<i>MED</i> Therapeutics, LLC.
: Our studies did not include human participants or human data. Archived human brain samples were analyzed with institutional permission under the state of California and NIH guidelines. Informed consent was obtained according to procedures approved by Institutional Review Boards at the University of California, San Diego, School of Medicine, and The Scripps Research Institute. All animal experimental procedures were approved by the Animal Care and Use Committee of Sejong University and were conducted following the guidelines of the Care and Use of Laboratory Animals.