Article History
Received: 10 June 2021
Revised: 22 October 2021
Accepted: 27 October 2021
First Online: 9 November 2021
Competing interests
: The authors declare no competing interests.
: Clinical tissue samples were obtained from The Second Xiangya Hospital of Central South University. This study was approved by the Medical Ethic Committee of The Second Xiangya Hospital of Central South University and performed in accordance with the Declaration of Helsinki. All participants have informed consent and their privacy has been fully protected. All of the animal experiments were conducted according to the Guidelines for Animal Health and Use (Ministry of Science and Technology, China, 2006). Animal experiments were conducted with the approval of the Animal Care and Use Committee of The Second Xiangya Hospital of Central South University.