Palomar-Siles, Mireia
Heldin, Angelos
Zhang, Meiqiongzi
Strandgren, Charlotte
Yurevych, Viktor http://orcid.org/0000-0003-2805-2454
van Dinter, Jip T.
Engels, Sem A. G.
Hofman, Damon A. http://orcid.org/0000-0003-4411-4563
Öhlin, Susanne
Meineke, Birthe
Bykov, Vladimir J. N. http://orcid.org/0000-0002-7199-8942
van Heesch, Sebastiaan http://orcid.org/0000-0001-9593-1980
Wiman, Klas G. http://orcid.org/0000-0002-7113-524X
Article History
Received: 24 May 2022
Revised: 8 November 2022
Accepted: 10 November 2022
First Online: 25 November 2022
Conflict of interest
: V.J.N.B. and K.G.W. are co-founders and shareholders of Aprea Therapeutics, a company that develops p53-based cancer therapy including APR-246. V.J.N.B. is employed by Aprea Therapeutics as data science consultant. K.G.W. is a member of its Clinical Advisory Board. Research in the K.G.W. lab has received financial support from Aprea Therapeutics. K.G.W. has received a salary from Aprea Therapeutics.
: All animal studies were approved by the Stockholm Animal Experiments Ethical Committee, Sweden (Dnr 7054-2019; Dnr 15763-2020).